Peptides for immune support
4 peptides used for immune support and inflammation, ranked by how much human research backs each one. Status, lab purity and mixing math for every one. Educational, not medical advice.
Ranked by evidence
Thymosin Alpha-1
Immune-modulating peptide approved in dozens of countries.
Multiple RCTs in hepatitis and sepsis; mixed results in sepsis (large trial neutral).
LL-37
The human body's own antimicrobial peptide, cut from cathelicidin.
Small human trials of topical LL-37 for venous leg ulcers; a larger Phase IIb missed its overall goal. No human data for injection.
VIP
A 28-amino-acid neuropeptide that relaxes blood vessels and calms inflammation.
Real human data (ED approval in the UK, small lung studies, a large COVID RCT that failed). CIRS nasal use is small open-label work only.
KPV
A three-amino-acid anti-inflammatory fragment of α-MSH.
Cell and mouse colitis studies (e.g. Dalmasso 2008, Gastroenterology). No published human trials.
Ranked by human evidence (how we rate it), then FDA approval. Higher isn’t a recommendation to use anything.
Compare them head to head
Common questions
What is the best-researched peptide for immune support and inflammation?
Thymosin Alpha-1, rated 4/5 for human evidence: Multiple RCTs in hepatitis and sepsis; mixed results in sepsis (large trial neutral).
Are any peptides for immune support and inflammation FDA approved?
No. None of the 4 peptides here is FDA approved for this use; most are sold as research chemicals.
Which are banned in sport?
WADA bans LL-37, KPV.
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