Thymosin Alpha-1
Immune-modulating peptide approved in dozens of countries.
Overview
A 28-amino-acid peptide produced naturally by the thymus. As Zadaxin (thymalfasin) it is approved in about 35 countries for hepatitis B/C and as a vaccine adjuvant, and has been studied in sepsis and cancer support.
How it works
Enhances T-cell maturation and dendritic cell function, modulating innate and adaptive immunity.
Evidence
4/5
Multiple RCTs in hepatitis and sepsis; mixed results in sepsis (large trial neutral).
Half-life
About 2 hours
Known as
Tα1, Thymalfasin, Zadaxin
Compound facts
- Type
- Synthetic acetylated polypeptide
- CAS Number
- 62304-98-7
- Molecular Formula
- C129H215N33O55
- Molecular Weight
- 3108.3 g/mol
- Amino Acids
- 28
- Sequence
- Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN
Reported benefits
Immune enhancement
Raises T-cell function in clinical trials.
Hepatitis B / C support
Approved indication in several countries.
Vaccine response
Improved response in older or immunocompromised people.
“Anecdotal” means reported by users, not shown in controlled trials.
Community-reported regimens
Not recommendations. These are commonly cited ranges, shown so you can see what real-world use looks like.
| Plan | Dose | Frequency | Duration | Route |
|---|---|---|---|---|
| Clinical (Zadaxin) | 1600 mcg | 2× per week | 6–12 months in studies | Subcutaneous |
| Short course (community) Used around illness or stress. | 1600 mcg | 2× per week | 4–6 weeks | Subcutaneous |
Reconstitution calculator
Set up for Thymosin Alpha-1. Switch peptide or vial size any time.
1Mix
Add 2 mL water for 5 mg/mL
2Draw
Draw to 32 units = 0.32 mL = 1.6 mg
Drag the plunger to set your dose.
3Inject
Next site
Right belly, upper
Tap a site after you inject to keep a rotation.
Pinch the skin, stay 2 in. from the navel, then into a sharps bin.
- Doses per vial
- 6.3
- Vial lasts
- 22 days
- Good once mixed
- ~14 days
- Syringe
- 50-unit, 0.5 mL
The vial outlasts its ~14-day shelf life once mixed. A smaller vial wastes less.
Math only: concentration (mg/mL) = vial mg ÷ mL of water; units = dose (mg) ÷ concentration × 100. Always double-check against your own vial label and a clinician. This tool does not recommend a dose.
Reconstitution
Diluent: Sterile water or bacteriostatic water.
- Wipe both vial tops with an alcohol swab and let dry.
- Draw the diluent, then inject it slowly down the inside wall of the vial — never straight onto the powder.
- Swirl gently or let it sit; do not shake. Foam can damage peptides.
- Solution should be clear. Cloudy, stringy or discolored = discard.
- Common mix: 10 mg + 2 mL = 5 mg/mL (1.6 mg = 32 units).
Storage
Powder
Freezer / fridge
Keep sealed vial in the freezer (−20 °C) for long-term storage; fridge (2–8 °C) is fine for a few weeks. Keep dry and out of light.
After mixing
~14 days
Refrigerate at 2–8 °C. Never freeze after mixing. Keep upright, capped, and out of light.
Travel
Keep cool
Short trips at room temperature are generally fine for powder; keep mixed vials cold.
- Use within about two weeks.
Side effects & cautions
Reported side effects
- Mild injection-site pain
- Fatigue
- Rare flu-like symptoms
Cautions
- Avoid with organ transplant / immunosuppressant therapy.
- Caution with autoimmune disease.
FDA & international status
Not FDA-approved (approved in ~35 other countries)
Orphan designations have been granted, but no US approval. Approved as Zadaxin in China, Italy, Singapore and others.
Regulations change often — verify with the FDA, EMA, MHRA, Health Canada, TGA and WADA before acting.
Often paired with
BPC-157Immune + repair pairing sometimes used during recovery.
Where to buy
Thymosin Alpha-1 vials
Shop this product ↗| Size | Price | Per mg | Stock | Latest COA |
|---|---|---|---|---|
| 10 mg | $39.99 | $4.00 | In stockBuy ↗ | 99.92% pure, lot THA0001 ILS Labs, tested 2026-07-30 |
Amino Club list prices as of 2026-10-07, before promo codes. Multi-buy: 2+ units 5% off, 3+ units 7.5% off, 10+ units 40% off. Prices change; confirm on the product page. Mixing? Their bacteriostatic water is Amino H2O from $19.99.
Thymosin Alpha-1 at Amino Club
Check sizes, current price and the certificate of analysis (COA) on the product page. Sold for in-vitro research only.
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- Look for a batch-specific COA with HPLC purity (≥98%) and mass-spec identity.
- Typical vial sizes: 5, 10 mg.
FAQ
Same as Thymosin Beta-4?
No — different peptide with different functions (Tα1 immune; Tβ4 repair).