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Cognitive & Mood
A small angiotensin-derived compound with striking rat memory data and no human trials.
Cognitive & Mood
A capped Selank sold only as a ready-made nasal spray. Evidence is borrowed from Selank.
Dihexa is not FDA-approved and rated 2/5 for evidence; Adalank is not FDA-approved and rated 1/5. Dihexa has more human evidence behind it. Both are banned in sport by WADA. Both are used for cognitive & mood goals.
| Compare | Dihexa A small angiotensin-derived compound with striking rat memory data and no human trials. | Adalank A capped Selank sold only as a ready-made nasal spray. Evidence is borrowed from Selank. |
|---|---|---|
| Category | Cognitive & Mood | Cognitive & Mood |
| Evidence | 2/5Animal and cell data from one main research group. No published human trials. A related HGF-boosting drug from the same lineage (fosgonimeton) missed its main goal in a Phase 2/3 Alzheimer's trial. | 1/5No published research on Adalank. Effects are inferred from Selank's small Russian clinical trials. |
| FDA status | Not FDA-approved | Not FDA-approved |
| WADA (sport) | Banned | Banned |
| Also known as | PNB-0408, N-hexanoic-Tyr-Ile-(6)-aminohexanoic amide | Adalank Research Mist, N-acetyl Selank amidate |
| How it works | Binds hepatocyte growth factor (HGF) and strengthens its signal through the c-Met receptor, promoting new synapses and dendritic spines. HGF/c-Met is also a well-known cancer-growth pathway. | Assumed to work like Selank: influencing GABA signaling, slowing enkephalin breakdown, and affecting serotonin and BDNF. The effect of the end-caps has not been measured. |
| Half-life | Not established in humans | Unknown; marketed as longer-acting than Selank, unproven |
| Commonly reported doses |
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| Route | Oral or transdermal (most common); some inject | Intranasal |
| Good once mixed | ~14 days in the fridge | Ready-made spray |
| Top side effects |
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| Lowest research-listing price per mg | $3.60 (10 mg vial, 40% off) | $3.60 (15 mg vial, 40% off) |
| Latest lab purity | 99.54% (lot DHX0001) | 99.82% (lot SADL0001) |
Want a third? Add another peptide. Doses are commonly reported ranges, not recommendations.
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Dihexa is not FDA-approved and rated 2/5 for evidence; Adalank is not FDA-approved and rated 1/5. Dihexa has more human evidence behind it. Both are banned in sport by WADA. Both are used for cognitive & mood goals.
Dihexa: Not FDA-approved. Adalank: Not FDA-approved. Regulations change, so confirm with the FDA.
Dihexa is rated 2 out of 5: Animal and cell data from one main research group. No published human trials. A related HGF-boosting drug from the same lineage (fosgonimeton) missed its main goal in a Phase 2/3 Alzheimer's trial. Adalank is rated 1 out of 5: No published research on Adalank. Effects are inferred from Selank's small Russian clinical trials. The scale is explained on our methodology page.
Dihexa is banned by WADA, by name or as part of a named class. Adalank is banned by WADA, by name or as part of a named class.