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Cognitive & Mood
Calming nootropic peptide built from the immune peptide tuftsin.
Cognitive & Mood
A three-amino-acid Khavinson 'bioregulator' aimed at the brain.
Selank is not FDA-approved and rated 3/5 for evidence; Pinealon is not FDA-approved and rated 2/5. Selank has more human evidence behind it. Pinealon is banned in sport by WADA; Selank is not. Both are used for cognitive & mood goals.
| Compare | Selank Calming nootropic peptide built from the immune peptide tuftsin. | Pinealon A three-amino-acid Khavinson 'bioregulator' aimed at the brain. |
|---|---|---|
| Category | Cognitive & Mood | Cognitive & Mood |
| Evidence | 3/5Small Russian clinical trials in generalized anxiety; limited Western data. | 2/5Cell and animal studies from the developing group; one small uncontrolled human cohort. No placebo-controlled trials. |
| FDA status | Not FDA-approved | Not FDA-approved |
| WADA (sport) | Not on the Prohibited List | Banned |
| Also known as | TP-7 analog, Tuftsin analog | EDR, Glu-Asp-Arg |
| How it works | Modulates GABA signaling, enkephalin breakdown, and serotonin/BDNF expression; also influences cytokine balance. | Proposed to enter cells and interact with DNA to influence gene activity, and to reduce oxidative stress in neurons. These ideas come mainly from the developers' lab and are not independently confirmed. |
| Half-life | Short; effects last hours | Not well characterized; likely short |
| Commonly reported doses |
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| Route | Intranasal or subcutaneous | Subcutaneous |
| Good once mixed | ~21 days in the fridge | ~30 days in the fridge |
| Top side effects |
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| Lowest research-listing price per mg | $1.80 (10 mg vial, 40% off) | $3.00 (10 mg vial, 40% off) |
| Latest lab purity | 99.49% (lot SLK0001) | 99.90% (lot PIN0002) |
Want a third? Add another peptide. Doses are commonly reported ranges, not recommendations.
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Selank is not FDA-approved and rated 3/5 for evidence; Pinealon is not FDA-approved and rated 2/5. Selank has more human evidence behind it. Pinealon is banned in sport by WADA; Selank is not. Both are used for cognitive & mood goals.
Selank: Not FDA-approved. Pinealon: Not FDA-approved. Regulations change, so confirm with the FDA.
Selank is rated 3 out of 5: Small Russian clinical trials in generalized anxiety; limited Western data. Pinealon is rated 2 out of 5: Cell and animal studies from the developing group; one small uncontrolled human cohort. No placebo-controlled trials. The scale is explained on our methodology page.
Selank is not named on the WADA list, though the general rule on non-approved substances (S0) can still apply. Pinealon is banned by WADA, by name or as part of a named class.