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Cognitive & Mood
Calming nootropic peptide built from the immune peptide tuftsin.
Cognitive & Mood
Sleep-promoting peptide first isolated from rabbit brain in the 1970s.
Selank is not FDA-approved and rated 3/5 for evidence; DSIP is not FDA-approved and rated 2/5. Selank has more human evidence behind it. DSIP is banned in sport by WADA; Selank is not. Both are used for cognitive & mood goals.
| Compare | Selank Calming nootropic peptide built from the immune peptide tuftsin. | DSIP Sleep-promoting peptide first isolated from rabbit brain in the 1970s. |
|---|---|---|
| Category | Cognitive & Mood | Cognitive & Mood |
| Evidence | 3/5Small Russian clinical trials in generalized anxiety; limited Western data. | 2/5Mixed small human trials from the 1980s–90s; no modern RCTs. |
| FDA status | Not FDA-approved | Not FDA-approved |
| WADA (sport) | Not on the Prohibited List | Banned |
| Also known as | TP-7 analog, Tuftsin analog | Delta Sleep-Inducing Peptide |
| How it works | Modulates GABA signaling, enkephalin breakdown, and serotonin/BDNF expression; also influences cytokine balance. | Poorly understood; modulates stress hormones and sleep architecture. Short half-life. |
| Half-life | Short; effects last hours | About 7–8 minutes |
| Commonly reported doses |
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| Route | Intranasal or subcutaneous | Subcutaneous |
| Good once mixed | ~21 days in the fridge | ~14 days in the fridge |
| Top side effects |
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| Lowest research-listing price per mg | $1.80 (10 mg vial, 40% off) | $3.60 (5 mg vial, 40% off) |
| Latest lab purity | 99.49% (lot SLK0001) | 99.45% (lot DSP0001) |
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Selank is not FDA-approved and rated 3/5 for evidence; DSIP is not FDA-approved and rated 2/5. Selank has more human evidence behind it. DSIP is banned in sport by WADA; Selank is not. Both are used for cognitive & mood goals.
Selank: Not FDA-approved. DSIP: Not FDA-approved. Regulations change, so confirm with the FDA.
Selank is rated 3 out of 5: Small Russian clinical trials in generalized anxiety; limited Western data. DSIP is rated 2 out of 5: Mixed small human trials from the 1980s–90s; no modern RCTs. The scale is explained on our methodology page.
Selank is not named on the WADA list, though the general rule on non-approved substances (S0) can still apply. DSIP is banned by WADA, by name or as part of a named class.