Loading the comparison…
Loading the comparison…
Cognitive & Mood
A three-amino-acid Khavinson 'bioregulator' aimed at the brain.
Longevity & Skin
Tetrapeptide proposed to support telomerase and circadian rhythm.
Pinealon is not FDA-approved and rated 2/5 for evidence; Epithalon is not FDA-approved and rated 2/5. They have a similar amount of human evidence. Both are banned in sport by WADA. Pinealon is listed under Cognitive & Mood; Epithalon under Longevity & Skin.
Often used together: Both are Khavinson bioregulators and are often run in the same short course. No combined studies.
| Compare | Pinealon A three-amino-acid Khavinson 'bioregulator' aimed at the brain. | Epithalon Tetrapeptide proposed to support telomerase and circadian rhythm. |
|---|---|---|
| Category | Cognitive & Mood | Longevity & Skin |
| Evidence | 2/5Cell and animal studies from the developing group; one small uncontrolled human cohort. No placebo-controlled trials. | 2/5Mostly Russian research groups; independent replication lacking. |
| FDA status | Not FDA-approved | Not FDA-approved |
| WADA (sport) | Banned | Banned |
| Also known as | EDR, Glu-Asp-Arg | Epitalon, Epithalone, AEDG |
| How it works | Proposed to enter cells and interact with DNA to influence gene activity, and to reduce oxidative stress in neurons. These ideas come mainly from the developers' lab and are not independently confirmed. | Proposed to activate telomerase and boost melatonin production from the pineal gland. Mechanisms not confirmed by independent Western research. |
| Half-life | Not well characterized; likely short | Short |
| Commonly reported doses |
|
|
| Route | Subcutaneous | Subcutaneous |
| Good once mixed | ~30 days in the fridge | ~30 days in the fridge |
| Top side effects |
|
|
| Lowest research-listing price per mg | $3.00 (10 mg vial, 40% off) | $1.80 (10 mg vial, 40% off) |
| Latest lab purity | 99.90% (lot PIN0002) | 99.26% (lot EPI0002) |
Want a third? Add another peptide. Doses are commonly reported ranges, not recommendations.
Free for ChatGPT and Claude
Connect MyPeps to ChatGPT or Claude and ask follow-ups about Pinealon and Epithalon. It answers from these same pages, with links back here.
Pinealon is not FDA-approved and rated 2/5 for evidence; Epithalon is not FDA-approved and rated 2/5. They have a similar amount of human evidence. Both are banned in sport by WADA. Pinealon is listed under Cognitive & Mood; Epithalon under Longevity & Skin.
Pinealon: Not FDA-approved. Epithalon: Not FDA-approved. Regulations change, so confirm with the FDA.
Pinealon is rated 2 out of 5: Cell and animal studies from the developing group; one small uncontrolled human cohort. No placebo-controlled trials. Epithalon is rated 2 out of 5: Mostly Russian research groups; independent replication lacking. The scale is explained on our methodology page.
Pinealon is banned by WADA, by name or as part of a named class. Epithalon is banned by WADA, by name or as part of a named class.
Both are Khavinson bioregulators and are often run in the same short course. No combined studies. That describes how some people use them, not a recommendation.