Loading the peptide page…
Loading the peptide page…
A core cellular coenzyme that declines with age — popular for 'energy', thin on proof.
Last reviewed Oct 7, 2026 · How we rate evidence · Report an error
NAD+ is a coenzyme in every cell, needed for turning food into energy and for DNA-repair and sirtuin enzymes. Levels fall with age. It is not a peptide. Oral precursors (NR, NMN) reliably raise NAD+ levels in human trials, but evidence that injecting NAD+ itself improves health outcomes is very limited.
Shuttles electrons in energy metabolism and is consumed by sirtuins, PARPs (DNA repair) and CD38. Injected NAD+ is likely broken down to smaller precursors outside cells before being taken up, so how much reaches cells intact is unclear.
Evidence
2/5
Strong biology and mouse aging studies; human trials mostly test oral precursors (NR, NMN). Direct NAD+ injection/infusion has only small pharmacokinetic studies.
Half-life
Short in blood (minutes to hours); quickly broken down to precursors
Known as
Nicotinamide adenine dinucleotide, β-NAD, Coenzyme I
Compare NAD+ with: MOTS-cEpithalonGlutathioneor any other →
Mostly animal dataMost of the evidence is from animal or cell studies, with tiny or uncontrolled human reports at most.
Strong biology and mouse aging studies; human trials mostly test oral precursors (NR, NMN). Direct NAD+ injection/infusion has only small pharmacokinetic studies. How we rate evidence
Infusion studies show blood NAD+ rises; oral precursors do so in multiple RCTs.
Boosting NAD+ improved metabolic and aging markers in mice.
Commonly reported by users; not shown in controlled trials.
IV NAD+ is promoted for withdrawal support; evidence is limited to small, uncontrolled reports.
“Anecdotal” means reported by users, not shown in controlled trials. Sources
Not recommendations. These are commonly cited ranges, shown so you can see what real-world use looks like.
| Plan | Dose | Frequency | Duration | Route |
|---|---|---|---|---|
| Community-reported 50 mg is a common starting dose; inject slowly. Some go to 100 mg. | 50 mg | 2–3× weekly | 4–8 weeks | Subcutaneous |
| Community-reported daily low Lower doses are used to reduce flushing and cramping. | 25 mg | Once daily, 5 days a week | 4 weeks | Subcutaneous |
Set up for NAD+. Switch vial size any time. Educational math only, not dosing advice.
At a common mix of 500 mg of NAD+ in 5 mL of water (100 mg/mL), these commonly reported doses come to the following on a U-100 insulin syringe (100 units = 1 mL). They are examples of the arithmetic, not recommendations.
| Reported plan | Dose | Draw to | Volume |
|---|---|---|---|
| Community-reported | 50 mg | 50 units | 0.5 mL |
| Community-reported daily low | 25 mg | 25 units | 0.25 mL |
Concentration (mg/mL) = vial mg ÷ mL of water; units = dose (mg) ÷ concentration × 100. A different vial size or amount of water changes every number above.
Amino Club sells NAD+ as a research chemical. Its listings are research-use-only and not for human use; we show them for price tracking and their published lab reports.
Research-use-only listing — not for human use.
40% off through our link (code MYPEPSINFO applies automatically), until Dec 31, 2026.
| Size | Price | Per mg | Stock | Latest COA |
|---|---|---|---|---|
| 500 mg | $41.99 | $0.08 | In stock | 99.18% pure, lot NAD0002 ILS Labs, tested Jul 30, 2026 |
Research-use-only listing — not for human use.
40% off through our link (code MYPEPSINFO applies automatically), until Dec 31, 2026.
| Size | Price | Per mg | Stock | Latest COA |
|---|---|---|---|---|
| 750 mg | $29.99 | $0.04 | In stock | 99.58% pure, lot SNAD0001 ILS Labs, tested Aug 20, 2026 |
List price, checked daily since Oct 7.
| Oct 7, 2026 | $69.99 | |
| Oct 8, 2026 | $69.99 | |
| Oct 9, 2026 | $69.99 | |
| Oct 10, 2026 | $69.99 | |
| Oct 11, 2026 | $69.99 | |
| Oct 12, 2026 | $69.99 | |
| Oct 13, 2026 | $69.99 | |
| Oct 14, 2026 | $69.99 | |
| Oct 15, 2026 | $69.99 | |
| Oct 16, 2026 | $69.99 | |
| Oct 17, 2026 | $69.99 | |
| Oct 18, 2026 | $69.99 | |
| Oct 19, 2026 | $69.99 | |
| Oct 20, 2026 | $69.99 | |
| Oct 21, 2026 | $69.99 | |
| Oct 22, 2026 | $69.99 | |
| Oct 23, 2026 | $69.99 | |
| Oct 24, 2026 | $69.99 | |
| Oct 25, 2026 | $69.99 | |
| Oct 26, 2026 | $69.99 | |
| Oct 27, 2026 | $69.99 | |
| Oct 28, 2026 | $69.99 | |
| Oct 29, 2026 | $69.99 | |
| Oct 30, 2026 | $69.99 | |
| Oct 31, 2026 | $69.99 | |
| Nov 1, 2026 | $69.99 |
HPLC purity from each published lab report; lowest 99.18%.
| May 29, 2026 | 99.67% | lot NAD0001 |
| Jul 30, 2026 | 99.18% | lot NAD0002 |
Amino Club list prices as of Nov 1, 2026; sale prices include the 40% applied through our link. Multi-buy: 2+ units 5% off, 3+ units 7.5% off, 10+ units 40% off. Prices change; confirm on the listing.
An email when it’s back in stock, its price drops, a sale starts, or its FDA or WADA status changes.
Affiliate link: we may earn a commission at no cost to you. Disclosure
All NAD+ lab reports, lot by lot →
Diluent: Bacteriostatic water (0.9% benzyl alcohol) — allows multiple draws from one vial.
Amazon affiliate links. Disclosure
Powder
Freezer / fridge
Keep sealed vial in the freezer (−20 °C) for long-term storage; fridge (2–8 °C) is fine for a few weeks. Keep dry and out of light.
After mixing
~14 days
Refrigerate at 2–8 °C. Never freeze after mixing. Keep upright, capped, and out of light.
Travel
Keep cool
Short trips at room temperature are generally fine for powder; keep mixed vials cold.
There is no FDA-approved NAD+ injection. NAD+ injections and IV drips in clinics are compounded products. Oral NAD+ precursors (NR, NMN) are sold as dietary supplements, which is not drug approval. Research vials are unregulated.
Regulations change often — verify with the FDA, EMA, MHRA, Health Canada, TGA and WADA before acting.
Oral NR or NMN has the most human data for raising NAD+. Injections and IV are popular but less studied; nasal absorption is largely unknown.
A common reaction to delivering NAD+ quickly. Slower injection or lower doses usually reduce it.
No. It's a dinucleotide coenzyme made of two nucleotides. It's sold alongside peptides but is a different kind of molecule.
It depends on the mix. At a common mix of 500 mg of NAD+ in 5 mL of water (100 mg/mL), 50 mg is 50 units (0.5 mL) on a U-100 insulin syringe. The formula is dose in mg ÷ concentration in mg/mL × 100. Change the vial size or water in the calculator and the units update. This is math, not a dose recommendation.
Bacteriostatic water (0.9% benzyl alcohol) — allows multiple draws from one vial. A common mix is 500 mg + 5 mL, which gives 100 mg/mL. Less water makes a stronger mix and fewer units per dose; more water makes a weaker mix and more units. Pick the amount that lands your dose on an easy-to-read line.
Refrigerate at 2–8 °C. Never freeze after mixing. Keep upright, capped, and out of light. Plan on about 14 days once it is mixed, and discard it sooner if it turns cloudy or has particles. The calculator shows how long a vial lasts at your dose and flags a vial that outlasts its shelf life.
Evidence rating (2/5): Strong biology and mouse aging studies; human trials mostly test oral precursors (NR, NMN). Direct NAD+ injection/infusion has only small pharmacokinetic studies.
Legal status: There is no FDA-approved NAD+ injection. NAD+ injections and IV drips in clinics are compounded products. Oral NAD+ precursors (NR, NMN) are sold as dietary supplements, which is not drug approval. Research vials are unregulated.
See something wrong or out of date? Report an error and we’ll check it against the sources. How we review pages