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Recovery & Repair
Synthetic fragment of thymosin beta-4, used for whole-body recovery.
Recovery & Repair
The 'Wolverine stack' in one vial: local and whole-body repair together.
TB-500 is not FDA-approved and rated 2/5 for evidence; BPC-157 + TB-500 is not FDA-approved and rated 2/5. They have a similar amount of human evidence. Both are banned in sport by WADA. Both are used for recovery & repair goals.
| Compare | TB-500 Synthetic fragment of thymosin beta-4, used for whole-body recovery. | BPC-157 + TB-500 The 'Wolverine stack' in one vial: local and whole-body repair together. |
|---|---|---|
| Category | Recovery & Repair | Recovery & Repair |
| Evidence | 2/5Full-length Tβ4 has some human trials (eye, wound); TB-500 fragment is mostly animal and anecdotal. | 2/5No studies of the combination. Each part is mostly animal data with minimal human work. |
| FDA status | Not FDA-approved | Not FDA-approved |
| WADA (sport) | Banned | Banned |
| Also known as | Thymosin Beta-4 fragment, Tβ4 (Ac-SDKP / LKKTETQ region) | Wolverine stack, BPC/TB blend |
| How it works | Binds actin, helping cells migrate to injured tissue; promotes angiogenesis and reduces inflammation in models. Full-length thymosin beta-4 has been studied in dry eye and wound healing trials; the TB-500 fragment itself has little human data. | BPC-157 appears to boost growth-factor signaling and new blood vessels at injury sites. TB-500 binds actin and helps cells move into damaged tissue. They act on different pathways, which is the rationale for pairing them. |
| Half-life | Not well characterized; dosed twice weekly by convention | Short for both; dosed daily by convention |
| Commonly reported doses |
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| Route | Subcutaneous | Subcutaneous |
| Good once mixed | ~28 days in the fridge | ~28 days in the fridge |
| Top side effects |
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| Lowest research-listing price per mg | $2.40 (10 mg vial, 40% off) | $4.50 (20 mg vial, 40% off) |
| Latest lab purity | 99.51% (lot TB0002) | 99.52% (lot WLV0003) |
Want a third? Add another peptide. Doses are commonly reported ranges, not recommendations.
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TB-500 is not FDA-approved and rated 2/5 for evidence; BPC-157 + TB-500 is not FDA-approved and rated 2/5. They have a similar amount of human evidence. Both are banned in sport by WADA. Both are used for recovery & repair goals.
TB-500: Not FDA-approved. BPC-157 + TB-500: Not FDA-approved. Regulations change, so confirm with the FDA.
TB-500 is rated 2 out of 5: Full-length Tβ4 has some human trials (eye, wound); TB-500 fragment is mostly animal and anecdotal. BPC-157 + TB-500 is rated 2 out of 5: No studies of the combination. Each part is mostly animal data with minimal human work. The scale is explained on our methodology page.
TB-500 is banned by WADA, by name or as part of a named class. BPC-157 + TB-500 is banned by WADA, by name or as part of a named class.