Nicholas compares sermorelin, CJC-1295, tesamorelin and ipamorelin: the two GH signals they copy, their approval histories, the evidence behind each, and shared cautions.
Read the full post: Growth hormone secretagogues compared: ipamorelin, CJC-1295, tesamorelin and sermorelin
In this episode
- 00:00 Cold open and intro
- 00:40 Two different signals
- 01:06 Sermorelin: the original
- 01:27 CJC-1295: two drugs, one name
- 01:52 Tesamorelin: the strong trials
- 02:11 Ipamorelin: selective but never approved
- 02:27 Why pairing became popular
- 02:58 Shared cautions and WADA
- 03:14 Wrap-up and Amino Club code
Peptides covered
Tools and deals
- Free reconstitution and dosing calculator: mypeps.info/calculator
- Amino Club: 40% off with code MYPEPSINFO at aminoclub.com
Sources
- https://www.govinfo.gov/content/pkg/FR-2013-03-04/pdf/2013-04827.pdf
- https://www.aidsmap.com/news/jul-2006/lipodystrophy-study-halted-after-patient-death
- https://blogs.nejm.org/hiv-id-observations/index.php/tesamorelin-is-approved/2010/11/12/
- https://clinicaltrials.gov/study/NCT00672074
- https://www.wada-ama.org/en/prohibited-list
- Full source list in the blog post.
Educational information only, not medical advice. Talk to a licensed clinician before starting, stopping or changing any medication. Research-grade peptides are not FDA-approved drugs.