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Episode 16 · October 11, 2026 · 5:00

GLP-1 drugs, peptides and surgery: why anaesthetists want to know

Anaesthetists warn GLP-1 drugs and unapproved peptides like retatrutide can leave food in the stomach before surgery. Plus TRIUMPH-2, a Melanotan II melanoma case and stem cell lobbying.

Show notes

Australia's anesthesia college says people on GLP-1 injections or other weight-loss peptides should tell their anesthesia doctor before surgery. Nicholas walks through the UK study behind the warning, why research-grade retatrutide is a special blind spot, and the week's quick hits.

In this episode

  • 00:00 Theme, cold open and intro
  • 00:50 Lead story: ANZCA surgery warning
  • 01:23 The UK anesthesia study
  • 01:59 Why unapproved peptides like retatrutide matter
  • 02:42 Quick hits: TRIUMPH-2, Melanotan II case, stem cells
  • 03:44 The flip side and what this means for you
  • 04:17 Wrap-up and Amino Club code

Peptides covered

Free tools

Sources

  1. Warning on weight-loss injections and peptides for patients having surgery — ANZCA via Medianet, October 5, 2026. https://newshub.medianet.com.au/2026/10/warning-on-weight-loss-injections-and-peptides-for-patients-having-surgery/174819/
  2. Weight-loss GLP-1 jabs like Ozempic and unapproved peptides pose 'serious' surgery risk — ABC News, October 7, 2026. https://www.abc.net.au/news/2026-10-07/peptides-ozempic-surgery-warning/107233212
  3. GLP-1 receptor agonists: clinical practice recommendations — ANZCA. https://www.anzca.edu.au/safety-and-advocacy/standards-of-practice/clinical-practice-recommendations-regarding-patients-taking-glp-1
  4. Peri-operative glucagon-like peptide-1 receptor agonist use and outcomes: a national prospective multicentre cohort study (El-Boghdadly et al.) — Anaesthesia, via EurekAlert, September 16, 2026. https://www.eurekalert.org/news-releases/1144100
  5. Retatrutide in adults with obesity and type 2 diabetes (TRIUMPH-2): a phase 3 trial — The Lancet, September 29, 2026. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01861-1/abstract
  6. New triple agonist retatrutide produces substantial weight loss in people living with obesity and type 2 diabetes — EurekAlert, September 29, 2026. https://www.eurekalert.org/news-releases/1145754
  7. Man injects gym-bought tanning peptide, gets a new melanoma — Gizmodo, October 8, 2026. https://gizmodo.com/man-injects-gym-bought-tanning-peptide-gets-a-new-melanoma-2000823544
  8. Are stem cells the next peptides? These advocates think RFK Jr. could make it happen — STAT, October 5, 2026. https://www.statnews.com/2026/10/05/stem-cell-industry-seeks-fda-regulation-like-peptides/

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Educational information only, not medical advice. Talk to a licensed clinician before starting, stopping or changing any medication. Research-grade peptides are not FDA-approved drugs. Nicholas and Brock are AI-generated voices; every episode is reviewed by our editor, Ryan E., MS.

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GLP-1 drugs, peptides and surgery: why anaesthetists want to know

Anaesthetists warn that GLP-1 injections and unapproved peptides like retatrutide can leave food in the stomach before surgery. Here's what the data shows.

This is educational information, not medical advice. Nicholas and Brock are AI-generated voices; every episode is reviewed by our editor, Ryan E., MS.